VIAJE DE INVESTIGACIÓN
Explore una colección de publicaciones de investigación de Debora Sobreira y colaboradores, que muestra su último trabajo innovador y se remonta a sus primeras contribuciones como estudiante de posgrado.
LISTA COMPLETA DE PUBLICACIONES
Glunk, V.*, Laber, S.*, Sinnott-Armstrong, N.*, Sobreira, D.R.*, Strobel, S.M.*, Nemati, B., Ebert, H., Ott, B., Garborcauskas, G., Honecker, J., Stirling, D., Deodato, G., Laumen, H., Abdenur, N., Calabuig, V., Ocvirk, S., Pfluger, P., Cimini, .B, Carpenter, A., Dankel, S.N., Pritchard, J., Lindgren, C.M., Hauner, H., Nobrega, M.A. and Claussnitzer, M. “A non-coding variant linked to metabolic obesity with normal weight affects actin remodeling in subcutaneous adipocytes," Nat Metab. 5; 861-879 (2023). *equal contribution / alphabetic order.
Chung, J., Das, A., Sun, X., Sobreira, D.R., Leung, Y.Y,, Iguarta, C., Mozaffari, S., Chou, Y.F., Thiagalingam, S., Mez, J., Zhang, Z., Jun, G.R., Kunkle, B., Martin, E.R., Pericak-Vance, A.M., Mayeux, R., Haines, J.L., Schellenberg, G., Nobrega, M.A., Lunetta, K.L., Pinto, J.M., Wang, L.S., Ober, C., and Farrer, L.A. “Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer disease among women,” Alzheimers Dement. 10.1002/alz.12719 (2022).
Joslin, A.C.*+ Sobreira, D.R.*+, Hansen, G.T., Sakabe, N.J., Aneas, I., Montefiori, L.E., Farris, K.M., Jing, G., Lehman, D., Ober, C., He, X. and Nobrega MA+. “A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci,” Nat Commun. 6;12(1):5253 (2021). *equal contribution. +corresponding author.
Aneas, I., Decker, D., Howard, C., Sobreira, D.R., Sakabe, N.J., Blaine, K., Stein, M., Hrusch, C., Montefiori, L.E., Tena, J.J., Magnaye, K., Clay, S., Gern, J., Jackson, D., Altman, M., Naurekas, E., Hogarth, D., White, S., Gómez-Skarmeta, J.L., Schoettler, N., Ober, C., Sperling, A., and Nobrega MA+. “Asthma-associated genetic variants induce IL33 differential expression through a novel regulatory region,” Nat Commun. 21;12(1):6115 (2021).
Sobreira, D.R.+, Joslin, A.C., Zhang, Q., Williamson, I., Hansen, G.T., Farris, K.M., Sakabe, N.J., Sinnott-Armstrong, N., Bozek, G., Jensen-Cody, S.O., Flippo, K.H., Ober, C., Bickmore, W.A,, Potthoff, M., Chen, M., Claussnitzer, M., Aneas, I. and Nóbrega, M.A+. “Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5,” Science. 4;372(6546):1085-1091 (2021) +corresponding author.
Sakabe, N.J., Aneas, I., Knoblauch, N., Sobreira, D.R., Clark, N., Paz, C., Horth, C., Ziffra, R., Kaur, H., Liu, X., Anderson, R., Morrison, J., Cheung, V.C., Grotegut, C., Reddy, T.E., Jacobsson, B., Hallman, M., Teramo, K., Murtha, A., Kessler, J., Grobman, W., Zhang, G., Muglia, L.J., Rana, S., Lynch, V.J., Crawford, G.E., Ober, C., He, X. and Nóbrega, M.A. “Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth,” Sci Adv. 2;6(49):eabc8696 (2020).
Helling, B.A., Sobreira, D.R., Hansen, G.T., Sakabe, N.J., Luo, K., Billstrand, C., Laxman, B., Nicolae, R.I., Nicolae, D.L., Bochkov, Y.A., Gern, J.E., Nobrega, M.A., White, S.R. and Ober, C. “Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma,” Commun Biol. 13;3(1):678 (2020).
El Khattabi, L., Zhao, H., Kalchschmidt, J., Young, N., Jung, S., Van Blerkom, P., Kieffer-Kwon, P., Kieffer-Kwon, K.R., Park, S., Wang, X., Krebs, J., Tripathi, S., Sakabe, N., Sobreira, D.R., Huang, S.C., Rao, S.S.P., Pruett, N., Chauss, D., Sadler, E., Lopez, A., Nóbrega, M.A., Aiden, E.L., Asturias, F.J., and Casellas, R. “A pliable mediator acts as a functional rather than an architectural bridge between promoters and enhancers,” Cell. 22;178(5):1145-1158.e20 (2019).
Boogerd, C.J., Xiaoming, Z., Aneas, I., Sakabe, N.J., Zhang, L., Sobreira, D.R., Montefiori, L.E., Bogomolovas, J., Joslin, A.C., Zhou, B., Chen, J., Nobrega, M.A. and Evans, S.M. “Tbx20 is required in mid-gestation cardiomyocytes and plays a central role in atrial development,” Circ Res. 3;123(4):428-442 (2018).
Nicodemus-Johnson, J., Myers, R.A., Sakabe, N.J., Sobreira, D.R., Hogarth, D.K., Naureckas, E.T., Sperling, A.I., Solway, J., White, S.R., Nobrega, M.A., Nicolae, D.L., Gilad, Y. and Ober, C. “DNA methylation in lung cells is associated with asthma endotypes and genetic risk,” JCI Insight. 8;1(20):e90151 (2016).
Smemo, S., Tena, J.J., Kim, K.H., Gamazon, E.R., Sakabe, N.J., Gómez-Marín, C., Anea, I., Credidio, F.l., Sobreira, D.R., Wasserman, N.F., Lee, J.H., Puviindran, V., Tam, D., Shen, M., Son, J.E., Vakili, N.A., Sung, H.K., Naranjo, S., Acemel, R.D., Manzanares, M., Nagy, A., Cox, N.J., Hui, C.C., Gomez-Skarmeta, J.L. and Nóbrega, M.A. “Obesity-associated variants within FTO form long-range functional connections with IRX3,” Nature. 20: 371-375 (2014).
Lours-Calet, C., Alvares, L.E., El-Hanfy, A.S., Gandesha, S., Walters, E.H., Sobreira, D.R., Wotton, K.R., Jorge, E.C., Lawson, J.A., Kelsey, L.A., Tada, M., Sharpe, C., Kardon, G. and Dietrich. S. “Evolutionarily conserved morphogenetic movements at the vertebrate head-trunk interface coordinate the transport and assembly of hypopharyngeal structures,” Dev Biol. 15;390(2):231-46 (2014).
Sensiate, L.A.*, Sobreira, D.R.*, Da Veiga, F.C., Peterlini, D.J., Pedrosa, A.V., Rirsch, T, Joazeiro, P.P., Schubert, F.R., Collares-Buzato, C.B., Xavier-Neto, J., Dietrich, S. and Alvares LE. “Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF-beta signaling pathways during chicken limb development,” Dev Dyn. 243(3):428-39 (2013). *equal contribution