Débora is a passionate geneticist with a specialization in human genetics, developmental biology, and gene regulation. Her primary focus revolves around advancing our knowledge of non-coding genetic variations and their impact on biological processes. With a deep curiosity for the intricacies of the genome, Débora is dedicated to unraveling the mysteries of non-coding regions and their role in shaping development, disease susceptibility, and overall genetic diversity.
Débora completed her M.Sc research at the University of Campinas in Brazil, studying the role of Dact 1 and Dact2 during mesoderm and ectoderm development. This experience ignited her curiosity about the fundamental regulatory mechanisms governing multi-potent mesodermal precursor cells, particularly in the context of limb birth defects and human diseases. Driven by her passion for understanding the genetic control of human limb development, she pursued her Ph.D., at the University of Campinas, aiming to unravel the intricate interplay between modulators of WNT and TGF-β signaling during limb development, thereby shedding light on the underlying intracellular regulatory networks. Throughout her doctoral studies, Débora was fascinated by the process of gene regulation during development and its pivotal role in orchestrating the precise temporal and spatial expression of genes. This fascination sparked her interest in investigating how gene regulation can help an organism respond to its environment and also contribute to diseases. To further expand her research expertise, Débora pursued a postdoctoral position at the Nobrega Lab at the University of Chicago. During her postdoc, she focused on developing an empirical framework to study the complex architecture of traits. Her work involved employing a diverse range of methodologies, including functional genomics and the development of innovative platforms for linking genetic variants to their functional consequences. Through her research, Débora aimed to uncover key insights into the intricate interplay between genetic variation and phenotypic outcomes, ultimately advancing our understanding of the genetic underpinnings of complex traits. Débora is not only driven by her scientific pursuits but also by her passion for promoting inclusivity in science and enhancing the training experience for students in Genomics and Genetics. She firmly believes in creating a more equitable and diverse scientific community where everyone has an opportunity to thrive. In recognition of her efforts, she was nominated as one of the 100 inspiring Hispanic/Latinx scientists in America. Beyond the walls of the lab, you'll likely find her exploring museums, appreciating art and history. She also has a green thumb and enjoys taking care of her plants. In the kitchen, Débora takes a scientific approach to her cooking and baking, experimenting with flavors and techniques to create delicious Brazilian dishes. And of course, she never goes without her trusty cup of coffee, which fuels her curiosity and energizes her throughout her scientific and personal endeavors.
Postdoctoral Researcher
Hanna Liliom
Pronouns: she/her/hers
Hanna has a background in neuroscience, holding an MSc and a PhD from Eötvös Loránd University in Hungary. She conducted research under the guidance of Dr. Katalin Schlett, exploring neuronal signaling pathways and the cellular response to oxidative stress. Hanna also gained expertise in human stem cells and induced neuronal models while working with Dr. Kristin K. Baldwin at Columbia University during her first postdoc research. During this time , she co-led a pipeline focused on inducing human fibroblasts into specific neuronal subtypes. Currently, in her second post-doctoral position at the Sobreira Lab, Hanna's research focuses on genetic and epigenetic analyses. She investigates the functional implications of genetic variants in human GWAS, particularly in relation to human-specific brain disorders, across diverse backgrounds. Outside of her work, Hanna enjoys birdwatching and spending time in nature.
Postdoctoral Researcher
Pronouns: she/her/hers
Gabriela graduated in Nutrition from UNIRIO, Brazil, with expertise in Food Science and Technology, particularly in characterizing bioactive compounds in Brazilian fruits. She obtained her PhD in Experimental Nutrition from USP, focusing on nutrient-epigenome interaction and its connection to obesity during the male pre-conception period. Gabriela is currently a post-doctoral researcher at the Laboratory of Nutritional Genomics and Inflammation, USP. Her project involves developing a polygenic risk score for energy intake regulation, correlating it with data from a population-based study in São Paulo, Brazil. Additionally, she's a visiting postdoctoral fellow at the Sobreira Lab, working on validating the score in the California population using Perturb-seq technology. In her spare time, Gabriela enjoys traveling, spending time with her family and her dog, Fred, and enjoying tennis and cycling.
Gabriela Pascoal
Graduate Student
Kailee Yoshimura
Pronouns: she/her/hers
Kailee is a graduate student in the Cell and Developmental Biology home area under MBI. She is originally from Hawaii, where she obtained her bachelors in Cell Biology at University of Hawaii at Hilo. In the Sobreira Lab, Kailee focuses on the integration of functional analyses with polygenic risk scores with the goal to improve its predictive capability in regards to obesity. In her free time she enjoys traveling, binge watching shows, hanging out with friends, and trying new restaurants.
Seolyn (Lynn) Yang
Graduate Student
Pronouns: she/her/hers
Lynn is a graduate student in the Gene Regulation, Epigenomics and Transcriptomics home area under MBI. Originally from Seoul, Korea, she moved to LA for her Bachelor’s and Master’s studies at USC, where she investigated transcription factors and differentially-bound enhancers in various cancer types. Lynn’s main focus in the Sobreira Lab at UCLA is to manipulate regulatory regions relevant to obesity and disease using CRISPR technology. In her free time, she enjoys traveling, going to concerts, hanging out with friends and family (cat included), and eating good food.
Graduate Student
Shreya Kordale
Pronouns: she/her/hers
Shreya is a graduate student in the Gene Regulation, Epigenomics, and Transcriptomics home area. She got her Bachelor’s in Microbiology, Chemistry, and Zoology from St. Joseph’s College in Bangalore, India. Following that she obtained her Master’s in Biomedical Science Research from the University of Bristol, UK. She did a post-baccalaureate research program at the National Cancer Institute developing a CRISPR-based approach to studying alternative splicing in mammalian cells. In the Sobreira Lab, Shreya focuses on using iPSC-derived cells and multi-omics approaches to investigate polycystic ovarian syndrome. In her free time, Shreya loves cooking, dancing, volunteering, and spending time with friends.
Meli Renteria
Post-bacc Student
Pronouns: she/her/hers
Meli is a SoCal native. She recently earned a B.S. in Molecular, Cell and Developmental Biology from UCLA and minoring in Biomedical Research. She has been involved in atrial fibrillation, hypertension, and renal denervation therapy research. In addition, she gained experience working with a team in the biodesign process for patients managing peritoneal dialysis with DxD Health Tech at Stanford University. In the Sobreira Lab, she is investigating how genetic variations influence development and function of adipocytes in complex diseases, such as obesity. In her free time, she enjoys reading, dancing, spending time with family and enjoying the local beaches.
Undergraduate Student
Candace Baik
Pronouns: she/her/hers
Candace is a Bioengineering undergraduate student from SoCal. In the Sobreira Lab, she is assisting Kailee in her research into polygenic risk scores for obesity. Post graduation, she hopes to work in the gene therapy/genetic engineering industry. Outside of the Sobreira Lab, she is also involved in the Society of Women Engineers (SWE) and the Biomedical Engineering Society (BMES). In her free time, she enjoys cooking, baking, and hiking the local trails with friends and family.